Term

class pronto.Term[source]

A term, corresponding to a node in the ontology graph.

Formally a Term frame is equivalent to an owl:Class declaration in OWL2 language. However, some constructs may not be possible to express in both OBO and OWL2.

Term should not be manually instantiated, but obtained from an existing Ontology instance, using either the create_term or the get_term method.

__eq__(other: Any) → bool

Return self==value.

__ge__(other)

Return self>=value.

__gt__(other)

Return self>value.

__hash__()

Return hash(self).

__le__(other)

Return self<=value.

__lt__(other)

Return self<value.

__repr__()

Return repr(self).

add_synonym(description: str, scope: Optional[str] = None, type: Optional[pronto.synonym.SynonymType] = None, xrefs: Optional[Iterable[pronto.xref.Xref]] = None) → pronto.synonym.Synonym

Add a new synonym to the current entity.

Parameters
  • description (str) – The alternate definition of the entity, or a related human-readable synonym.

  • scope (str or None) – An optional synonym scope. Must be either EXACT, RELATED, BROAD or NARROW if given.

  • type (SynonymType or None) – An optional synonym type. Must be declared in the header of the current ontology.

  • xrefs (iterable of Xref, or None) – A collections of database cross-references backing the origin of the synonym.

Raises

ValueError – when given an invalid synonym type or scope.

Returns

Synonym – A new synonym for the terms. The synonym is already added to the Entity.synonyms collection.

property alternate_ids

A set of alternate IDs for this entity.

Type

frozenset of str

property annotations

Annotations relevant to the entity.

Type

frozenset of PropertyValue

property anonymous

Whether or not the entity has an anonymous id.

Semantics of anonymous entities are the same as B-Nodes in RDF.

Type

bool

property builtin

Whether or not the entity is built-in to the OBO format.

pronto uses this tag on the is_a relationship, which is the axiomatic to the OBO language but treated as a relationship in the library.

Type

bool

property comment

A comment about the current entity.

Comments in comment clauses are guaranteed to be conserved by OBO parsers and serializers, unlike bang comments. A non None comment is semantically equivalent to a rdfs:comment in OWL2. When parsing from OWL, several RDF comments will be merged together into a single comment clause spanning over multiple lines.

Type

str or None

property created_by

the name of the creator of the entity, if any.

This property gets translated to a dc:creator annotation in OWL2, which has very broad semantics. Some OBO ontologies may instead use other annotation properties such as the ones found in Information Interchange Ontology, which can be accessed in the annotations attribute of the entity, if any.

Type

str or None

property creation_date

the date the entity was created.

Type

datetime or None

property definition

the textual definition of the current entity.

Definitions in OBO are intended to be human-readable text describing the entity, with some additional cross-references if possible.

Type

str or None

property disjoint_from

The entities declared as disjoint from this entity.

Two entities are disjoint if they have no instances in common. Two entities that are disjoint cannot share any subentities, but the opposite is not always true.

Type

EntitySet

property equivalent_to

The entities declared as equivalent to this entity.

Type

EntitySet

property id

The OBO identifier of the entity.

Identifiers can be either prefixed (e.g. MS:1000031), unprefixed (e.g. part_of) or given as plain URLs. Identifiers cannot be edited.

Type

str

property name

The name of the entity.

Names are formally equivalent to rdf:label in OWL2. The OBO format version 1.4 made names optional to improve OWL interoperability, as labels are optional in OWL.

Type

str or None

property namespace

the namespace this entity is defined in.

Type

str or None

property obsolete

whether or not the entity is obsolete.

Type

bool

property subsets

the subsets containing this entity.

Type

frozenset of str

property synonyms

a set of synonyms for this entity.

Type

frozenset of Synonym

property xrefs

a set of database cross-references.

Xrefs can be used to describe an analogous entity in another vocabulary, such as a database or a semantic knowledge base.

Type

frozenset of Xref

objects(r: pronto.relationship.Relationship) → Iterator[pronto.term.Term][source]

Iterate over the terms t verifying self · r · t.

Example

>>> go = pronto.Ontology.from_obo_library("go.obo")
>>> go['GO:0048870']
Term('GO:0048870', name='cell motility')
>>> list(go['GO:0048870'].objects(go['part_of']))
[Term('GO:0051674', name='localization of cell')]

Todo

Make Term.objects take in account holds_over_chain and transitive_over values of the relationship it is building an iterator with.

superclasses(distance: Optional[int] = None, with_self: bool = True) → pronto.logic.lineage.SuperclassesHandler[source]

Get an handle over the superclasses of this Term.

In order to follow the semantics of rdf:subClassOf, which in turn respects the mathematical definition of subset inclusion, is_a is defined as a reflexive relationship, and so is its inverse relationship.

Parameters
  • distance (int, optional) – The maximum distance between this term and the yielded superclass (0 for the term itself, 1 for its immediate superclasses, etc.). Use None to explore transitively the entire directed graph.

  • with_self (bool) – Whether or not to include the current term in the terms being yielded. RDF semantics state that the rdfs:subClassOf property is reflexive, so this is enabled by default, but in most practical cases only the distinct subclasses are desired.

Yields

Term – Superclasses of the selected term, breadth-first. The first element is always the term itself, use itertools.islice to skip it.

Example

>>> ms = pronto.Ontology.from_obo_library("ms.obo")
>>> sup = iter(ms['MS:1000143'].superclasses())
>>> next(sup)
Term('MS:1000143', name='API 150EX')
>>> next(sup)
Term('MS:1000121', name='SCIEX instrument model')
>>> next(sup)
Term('MS:1000031', name='instrument model')

Note

The time complexity for this algorithm is in \(O(n)\), where \(n\) is the number of subclasses of initial term.

See also

The RDF Schema 1.1 specification, defining the rdfs:subClassOf property, which the is_a relationship is translated to in OWL2 language.

subclasses(distance: Optional[int] = None, with_self: bool = True) → pronto.logic.lineage.SubclassesHandler[source]

Get an handle over the subclasses of this Term.

Parameters
  • distance (int, optional) – The maximum distance between this term and the yielded subclass (0 for the term itself, 1 for its immediate children, etc.). Use None to explore the entire directed graph transitively.

  • with_self (bool) – Whether or not to include the current term in the terms being yielded. RDF semantics state that the rdfs:subClassOf property is reflexive, so this is enabled by default, but in most practical cases only the distinct subclasses are desired.

Yields

Term – Subclasses of the selected term, breadth-first. The first element is always the term itself, use itertools.islice to skip it.

Example

>>> ms = pronto.Ontology.from_obo_library("ms.obo")
>>> sub = iter(ms['MS:1000031'].subclasses())
>>> next(sub)
Term('MS:1000031', name='instrument model')
>>> next(sub)
Term('MS:1000121', name='SCIEX instrument model')
>>> next(sub)
Term('MS:1000122', name='Bruker Daltonics instrument model')

Hint

Use the to_set method of the returned iterator to efficiently collect all subclasses into a TermSet.

Note

This method has a runtime that is \(O(n)\) where \(n\) is the number of subclasses of the initial term. While OBO and OWL only explicit the superclassing relationship (equivalent to the rdfs:subClassOf property in RDF), we can build a cache that stores the edges of the resulting knowledge graph in an index accessible by both endpoints of each edge.

is_leaf() → bool[source]

Check whether the term is a leaf in the ontology.

We define leaves as nodes in the ontology which do not have subclasses since the subclassing relationship is directed and can be used to create a DAG of all the terms in the ontology.

Example

>>> ms = pronto.Ontology.from_obo_library("ms.obo")
>>> ms['MS:1000031'].is_leaf()   # instrument model
False
>>> ms['MS:1001792'].is_leaf()   # Xevo TQ-S
True

Note

This method has a runtime of \(O(1)\) as Ontology objects internally cache the subclasses of each term.

property intersection_of

The terms this term is an intersection of.

Type

frozenset